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[DOI] [PMC free article] [PubMed] [Google Scholar] Bao M

The phase 3 TRIUMPH-4 trial confirmed these findings

The nine compounds in this category span a structural range: peptide single agonists (semaglutide, liraglutide), peptide dual agonists (tirzepatide for GIP/GLP-1

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Tissue distribution favors areas with high GLP-1 and GIP receptor expression: pancreas, gut, brain, and adipose tissue