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We know that macrocytosis is a very, very late stage of B12 deficiency and that severely deficient patients may not present with this sign, the administration of folic acid also masks macrocytosis by normalising the size of the blood cells

Similarly, folate requirements rise during active cell division, and inadequate folate can limit the effectiveness of B12 therapy

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But somewhere in the middle of all this praise, a quiet concern goes unnoticed

The cost of cyanocobalamin is around $4 per vial using a free Drugs.com discount card

The copper ion in AHK-Cu is suggested to be involved in enzyme activity related to collagen and elastin synthesis