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That's because the more stress you experience, the more your body produces free radicals that circulate throughout your body, bumping and bashing against cells, increasing oxidative stress

Downregulation of glutathione biosynthesis contributes to oxidative stress and liver dysfunction in acute kidney injury

The science is actually quite fascinating: your skin produces melanin (the pigment that gives skin its colour), and sometimes this process goes a bit overboard, especially after sun exposure or hormonal changes

Andrology 8(1):148153

Proinflammatory and oxidative stress states induced by human papillomavirus and chlamydia trachomatis coinfection affect sperm quality in asymptomatic infertile men

Sci Immunol (2019) 4:eaay0555