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Donahue AC, Fruman DA

developed a novel CoMnFe-layered double oxides (LDO) nanosheet with multienzyme activities, which not only enhanced ROS production during radiotherapy but also catalyzed lactate into pyruvate

This condition can have a devastating effect whatever the cause

PAGln was identified through untargeted metabolomic analysis in a large-scale clinical study to be increased in circulation and associated with CV-related disease and major adverse cardiovascular events (i.e., stroke, myocardial infarction, and death) 11

These improvements in cardiovascular risk markers, combined with enhanced insulin sensitivity and glucose metabolism, suggest tesofensine may provide comprehensive metabolic benefits for obese individuals with comorbid metabolic conditions

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