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10.1097/CHI.0b013e3181799ee8 J Am Acad Child Adolesc Psychiatry

The Bigger Concern: Leaving a Deficiency Untreated When weighing the minimal risks of B12 injections, it helps to consider the well-documented risks of an untreated B12 deficiency

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When the gut environment is calm, vagal tone improves, shifting the autonomic nervous system away from the hyper-aroused "fight or flight" sympathetic state and toward the restorative "rest and digest" parasympathetic state