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Inactivation of DHODH in cancer cells with low GPX4 expression significantly increased intracellular lipid peroxidation, while in cancer cells with high GPX4 expression, DHODH inactivation synergized with inducers to enhance ferroptosis

USA 106 , 83508355 (2009)

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How should CARNISURE 1GM INJECTION be stored

Reported biochemical potency against human NNMT is in the low-micromolar range with cellular EC values in the low-micromolar range for suppression of 1-MNA and lipogenesis, with selectivity over related methyltransferases and NAD-salvage enzymes [1,6,7]

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line