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NICE recommends more frequent injections (alternate days until no further improvement) for patients with neurological involvement

doi: 10.1016/j.beem.2005.07.004

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NNMT catalyzes the methylation of nicotinamide, diverting it from the NAD+ salvage pathway

This makes it particularly effective for patients with absorption problems such as pernicious anaemia

Functional studies on native and mutated forms of perilipins: a role in protein kinase A-mediated lipolysis of triacylglycerols