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Untreated pyelonephritis progresses to sepsis in 10-20% of cases, particularly dangerous for pregnant women, diabetics, and immunocompromised patients who need immediate IV antibiotics

Experimental models have evaluated it for cytoprotective and regenerative activities across gastrointestinal mucosa, tendons, ligaments, muscles, bone, nervous tissue, and vascular endothelium

This approach involves additional sample preparation steps and data analysis compared to a standard analysis for measuring protein abundance

Growth factor signaling enhancement FGF pathway activation: Fibroblast growth factors (FGFs) support various cell types including retinal cells

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