Creatine is one of the most researched and well-tolerated supplements available, and it remains safe to use during a caloric deficit
[8] antioxidant action to protect cells from oxidative stress (caused by free radical toxicity) and damage
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Although the present work highlights the considerable potential of flavonoids as functional food-derived modulators of the gut microbiota NF-B axis in MASLD, their clinical translation remains constrained by limited bioavailability and heterogeneity across experimental models, highlighting the need for standardised dosing strategies, integrated host microbiota analyses, and well-designed human studies to substantiate clinical applicability
The present systematic review is unprecedented in its comprehensiveness and findings which contravene the previous presumptions
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