10.1161/ATVBAHA.109.193375 Arterioscler Thromb Vasc Biol
Additionally, another peak appeared at ~1440 cm 1 , indicating flexion vibration of the OH bond
Studies have shown that JAK2 may also phosphorylate insulin receptor substrate 1/2 (IRS1/2) and activate the phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) pathway (Ridderstrale et al., 1995
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On the other hand, compound QMT3 presents the second-best binding energy (-7.84 kcal/mol) and the lowest Ki value, which allows establishing a positive correlation between the binding energy and the inhibition constant
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