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Therefore, a simple way to reduce the pain of Botox injections is to practice deep breathing or meditation before and during the procedure

Environ Exp Bot 122:7884

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Because GH and IGF-1 signaling can influence fluid balance, connective tissue, metabolism, and glucose regulation, potential GH-axis-related effects include: Water retention Peripheral edema Joint stiffness or discomfort Muscle aches Paresthesias or tingling Carpal-tunnel-like symptoms Changes in insulin sensitivity or glucose handling Adult GH replacement literature consistently identifies fluid-retention-related effects including edema, arthralgia, carpal tunnel syndrome, and paresthesias as common side effects of GH treatment

10.1016/j.kint.2017.02.023 112 LinX.JinH.ChaiY.ShouS

Eur J Pharmacol 1981