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In contrast, during acute ethanol exposure, ethanol competes with APAP for Cyp2E1 metabolism, which reduces NAPQI formation as long as ethanol is present and attenuates liver injury [176]

Unlike NSAIDs, acetaminophen does not cause stomach irritation or increased bleeding risk, making it a preferred choice for individuals sensitive to gastrointestinal side effects

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Induction by interferon-gamma and contribution to ATP-dependent proteolysis