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Experimental Biology and Medicine, 245(15), 14171425

The upregulation of collagen VII was confirmed in human skin explants by immunohistological staining

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The frequency of Vitamin B12 injections varies from daily to monthly, depending on the treatment phase

Further support for these findings came from an ex vivo skin model, which also showed a notable increase in collagen 4 synthesis at the dermal-epidermal junction when exposed to the optimized GHK-Cu and LMW HA mixture