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Imerslund-Grsbeck syndrome (selective vitamin B12 malabsorption with proteinuria)

10.1016/j.ejphar.2011.05.038 50 IlicS.DrmicD.ZarkovicK.KolencD.CoricM.BrcicL.et al (2010)

It's a no-win situation unless you break this vicious circle and supplement the much-needed vitamins

In the duodenum, pancreatic enzymes break down haptocorrin which allows the pH change to trigger the transfer of B12 to the intrinsic factor (IF) which is a protein made by the stomach

Adenosine Triphosphate (ATP) is known as the energy molecule

The standard regimen involves 1 mg (1000 g) administered intramuscularly on alternate days until there is no further improvement in symptoms, followed by maintenance injections of 1 mg every two months