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It was shown that stimulation of PKC led to enhanced StAR expression and progesterone secretion in Leydig and granulosa cells (Figure 2) (121, 122)

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WADA additionally clarified that tetryzoline is considered an imidazoline derivative, and therefore, like other imidazoline derivatives, it is not prohibited when used in the ear (otic), in the eye (ophthalmic) or in the nose (nasal)