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In addition, hydroxocobalamin may be used as part of the treatment for cyanide poisoning (as an antidote), although in such emergency cases very high doses are administered under hospital care

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14 weeks Reduced tingling & burning for some patients 23 months Better sensation, improved balance, reduced pain 6 months+ Nerve repair and long-term function improvement Severe or long-standing neuropathy may require ongoing treatment

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This dosage-to-volume relationship affects absorption kinetics directly