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In such models, persistent corticosterone (CORT) treatment, exposure to erratic moderate stressors, and social defeat are standard techniques for producing depressive-like behaviors in animals

Liu YT, Sun J, Rao SQ, Su YJ, Yang YJ

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The solution isnt to avoid caloric restrictionits to actively counteract metabolic slowdown by increasing energy expenditure through targeted interventions

Comparison of CJC-1295 With DAC vs