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Acknowledgments This work was supported by the National Natural Science Foundation of China (30600661, 30872708, 30801174, 30871191 and 30900622), the Scientific Research Foundation of the Health Bureau of Hunan Province (B2007058), the Natural Science Foundation of Hunan Province (05C0163) and the Post-doctorate Scientific Research Special-purpose Project of Hunan Province (2008RS4012)

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doi:10.1080/07315724.2012.10720431

Both drugs negatively impact the adrenal glands, colon, and esophagus and are mutagenic (Castro et al

In a prospective study, Sabate et al.[39] estimated the incidence of acute liver injury due to therapeutic dosages of APAP to be about 10 per million user-years

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