CVB4 P2-C protein has sequence homologies to GAD, a T1D autoantigen, and is recognized by TCR receptors on T cells against GAD65 ( Figure 2 ) (191, 192)
But, if dietary changes dont resolve the vitamin deficiency, then a doctor may recommend supplementation through pills or injections, depending on the cause of the deficiency
Dosing recommendations vary based on the clinical indication and should follow UK guidance
Maturation of red blood cells from the immature megaloblasts produced in bone marrow is dependent on Vitamin B12, which is a precursor for co-enzyme B12 involved in important enzyme reactions in the production of components of folic acid, which in turn is essential for DNA synthesis
This helps maintain stable levels even when oral supplements are ineffective
A 10mg vial lasts 20 days