Figure S2: Longitudinal changes in the concentration of biochemical parameters (A) 8-OHdG, (B) Fasting Glucose, (C) PP Glucose, (D) HbA1c, (E) Fasting Insulin, and (F) PP Insulin in elderly diabetic subjects
Because GSH rapidly oxidizes outside cells, variables like collection time, processing delays, temperature, and anticoagulants significantly affect accurate measurement, particularly in the unstable reduced fraction of GSH [118]
MLO Targeting: The optimized sensor (miniGrx1-roGFP2) with a 20-amino-acid linker was targeted to specific MLOs (nucleoli, stress granules, p-bodies, nuclear paraspeckles, and Cajal bodies) and their surrounding environments (cytosol and nucleoplasm) using established localization signals
Regulation of membrane fusion in secretory exocytosis Annu Rev Physiol 1986
Provides an antioxidant that helps protect against oxidative stress
Wang, J., Beauchemin, M