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Two authors (EAA, CC) reviewed in an iterative process the results of individual studies to identify common themes and develop a structure for reporting the results

The cause of this central nervous system disease, which disrupts signals between the brain and other parts of the body, is unknown although many researchers think its the result of an autoimmune process

military superstition of flipping a lucky cigarette upside down is thought to have stemmed from troops during the war flipping a cigarette upside down in their packs

Smokers are two to four times more likely than nonsmokers to develop coronary heart disease, and 20%-40% of deaths from heart disease are directly attributable to smoking

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