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MBOAT1 and MBOAT2, newly identified negative regulators of ferroptosis, remodel membrane phospholipids to reduce their susceptibility to oxidation

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Six variants were observed to be damaged by using the SIFT tool and were further subjected to cross check by using five different tools (WHESS.db submodule PolyPhen-2 server, Mutation testers, SNPs&Go, SNAP2 and Provean tools)

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Future studies involving a systematic analysis of dipeptidasedipeptides relationships, in malignant and non-malignant tissues, are required

Xu P, Wang J, Hong F, et al