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Degeneration of spinal motor neurons by chronic AMPA-induced excitotoxicity in vivo and protection by energy substrates

It applies if their driving ability is impaired by alcohol or drugs

Gal3 is able to sense damaged lysosomes, where they accumulate to induce further lysophagy by recruiting autophagy regulatory factors, including uncoordinated-51-like kinase 1 (ULK1), Beclin 1, and autophagy-related protein 16L1 (ATG16L1) after binding with E3 ubiquitin ligase-tripartite domain containing protein 16 (TRIM16) 86

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