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Reconstitution: 3.0 mL bacteriostatic water per 600 mg vial gives 200 mg/mL (1 unit = 2 mg)

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As IKK- is the direct upstream kinase that phosphorylates IB-, leading to its degradation, we next examined whether decreased TNF-induced IB- phosphorylation by H 2 O 2 treatment was due to its effects on IKK- activity