doi: 10.1038/nrendo.2011.77
Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation
Systematic reviews note that existing human data comes largely from small observational studies or case reports, many with methodological limitations
Cell Longev 2019, 9084643
Research involving this compound typically focuses on neurotrophic signaling and synaptic pathway research, with attention to receptor activity, cellular signaling, and measurable pathway response in experimental models
Biochemical analysis of old (ages 67 3 years) and young (ages 27 2 years) human patellar tendons found aged tendons have decreased total collagen level, increased levels of both HP and LP enzymatic crosslinks, and increased pentosidine level (as a representative AGE), compared to young tendons (Coupp et al ., 2009)