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Our understanding of the means by which GH and IGF-1 regulate growth was set into motion after experiments conducted in 1957 by Salmon and Daughaday showed that a factor in the serum (sulfation factor) was able to stimulate sulfate incorporation into cartilage in vitro [137]

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Research Background In preclinical research settings, IGF-1 LR3 has been examined across laboratory models, often in the context of: Insulin-like growth factor signalling studies Receptor binding and cellular pathway investigations Peptide interaction and biological signalling research For published research references, consult public scientific databases such as PubMed

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