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Users and researchers have documented effects across several domains of health and performance, though it bears mentioning that much of this evidence comes from animal studies, small human trials, or anecdotal reports rather than large-scale clinical trials

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Constipation is another common issue, reported in 21-25% of retatrutide users and a significant percentage of cagrilintide users

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Some clinical studies have explored the use of glutathione in children as young as three to thirteen years old for specific health supports