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Medications Used for Endoscopy Drug FDA category Recommendations for pregnancy Recommendations for breastfeeding Ampicillin Benzocaine Diatrizoate Diazepam Electricity Epinephrine Fentanyl Flumazenil Glucagon Lidocaine Meperidine Midazolam Naloxone Piperacillin-tazobactam Polyethylene glycol electrolyte Propofol Simethicone Sodium glycol electrolyte B C D D None C C C B B B D B B C B C C Safe to use when required Avoid unless benefit outweighs risk Minimal use for therapeutic ERCP Midazolam is the preferred benzodiazepine Use for therapeutic ERCP Avoid unless for hemostasis Use in low doses Only for severe benzodiazepine overdose Avoid except for ERCP Gargle and spit (oral form) Use in low doses Use in low doses Only for severe narcotic overdoses Useful in cholangitis or biliary sepsis No human studies available Avoid in first and second trimesters Can be avoided but low risk Low risk with 1-time use Compatible No human data: potential toxicity Limited human data: probably compatible Limited human data: potential toxicity No human data: potential toxicity No human data: potential toxicity Compatible No human data: probably compatible No human data Limited human data: probably compatible Compatible Limited human data: potential toxicity No human data: probably compatible Safe Probably safe Limited human data: probably compatible No human data: probably compatible No human data Abbreviations: ERCP, endoscopic retrograde cholangiopancreatography