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Most users report visible improvements starting around 8 to 12 weeks of consistent injectable use, with optimal results building over 12 or more weeks of continuous administration

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However, with IBD-current biologic therapies, all these mean some patients primary non-responders, experience a loss of response, intolerance or side effects, defining the urgent unmet need for novel treatments (13, 14)

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Nilotinib is an orally available inhibitor of the BCR-ABL kinase and works by preventing the growth and proliferation of cancer cells, in turn inducing their death