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Some medication will still absorb through the GI tract, but at much lower bioavailability than sublingual absorption

Regular sterile water lacks this protection and should only be used for single-dose preparations

However, emerging KD modifications, such as the MAD or MCT-KD, have shown improved tolerability in some studies [199, 200], suggesting their potential for better long-term adherence

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Similarly, in newborn mice, P4 reduced inflammation and induced neuronal survival, suggesting that its effects involve regulating pro-inflammatory cytokines (108, 110)

Free Radic Biol Med (2021) 177:15666