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Pharmacological doses of thiamine benefit patients with the CharcotMarietooth neuropathy by changing thiamine diphosphate levels and affecting regulation of thiamine-dependent enzymes

Trowbridge says that new studies show that significant lab abnormalities are extremely rare and may not be necessary for healthy patients 38 39 as they typically resolve on their own without needing to stop the medication

To maintain rapid proliferation, these cells require efficient protein synthesis and amino acid metabolism (232)

Wainberg, Z

an active form, which exists in a dimertetramer equilibrium

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