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Accessed online at Richie JP Jr, Nichenametla S, Neidig W, et al

Recently, THSWD has been reported to ameliorate high-salt diet-induced hypertensive nephropathy by suppressing ferroptosis through the p53-NRF2-p21 signaling pathway [259]

Lifestyle factors with GST variants: Stop smoking and avoid second-hand smoke: Studies have linked the GSTM1 null genotype with a 46% increase in the risk of lung cancer in smokers.[ref] Avoid Radon: People with GSTM1 null genotypes are at a 3-fold increased risk of lung cancer with radon exposure.[ref] Access this content: An active subscription is required to access this content

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GSH serves as an electron donor to reduce ROS and is oxidized into glutathione disulfide (GSSG)