Optimizing Nutritional Levels Proper nutrition forms the backbone of reproductive health
10.1016/j.niox.2014.09.002 46 KumarR.CogganA
Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations A : amyloid AD: Alzheimer's disease AMS: 4-acetamido-4-maleimidyl-stilbene-2,2-disulfonate ASK1: apoptosis signal-regulating kinase 1 BCA: bicinchoninic acid CERAD: Consortium to establish a Registry for Alzheimer's disease Daxx: death-associated protein DSM-IV: Diagnostic and Statistical Manual of Mental Disorders-IV DTT: dithiothreitol ERK: extracellular signal-regulated kinase GFAP: glial fibrillary acidic protein GRX1: glutaredoxin 1 GSH: reduced glutathione GSSG: oxidized glutathione HIV: human immunodeficiency virus IGF-I: insulin-like growth factor-I JNK: c-Jun N-terminal kinase MAPKKK: mitogen-activated protein kinase kinase kinase MCB: monochlorobimane MEM: minimum essential medium MTT: 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2 H -tetrazolium bromide ORF: open reading frame PI3K: phosphatidylinositol 3-kinase PLSD: post least significant distance PMSF: phenylmethylsulfonyl fluoride TCA: trichloroacetic acid TRX1: thioredoxin 1 TRXR: thioredoxin reductase References Hardy JA and Higgins GA (1992) Alzheimer's disease: the amyloid cascade hypothesis
Biochemical and histological analyses were performed on the hippocampal and cortical tissue, assessing oxidative stress markers, antioxidant enzyme activity, and glial activation through spectrophotometric assays and immunohistochemistry
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Bacteriostatic saline adds 0.9% sodium chloride
