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Ethics statement The studies involving human participants were reviewed and approved by the Institutional Review Board of Peking University Shenzhen Hospital

These results suggest that a small fraction of dihexa undergoes enterohepatic recirculation, which could cause an increase in plasma levels

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Captopril has been revealed to facilitate the GSH system in several rodent models of myocardial injuries, such as clozapine and DOX-induced damage models, thereby protecting cardiomyocytes from oxidative stress [239, 240]

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Pyroptosis regulation Pyroptosis is a form of inflammatory programmed cell death distinct from apoptosis