is nicotine derived from tobacco New report highlights marketing of synthetic and “non-tobacco” products – Stanton Glantz blog Comparative effects of alternate tobacco

Science 194 , 10671069 (1976)

The relationship between the white English landowners, white servants, African servants, and the local indigenous people of the Powhatan Confederacy was never one of equality but grew strained and far more unequal as more land was required by the colonists for settlements and tobacco plantations which encouraged not only the displacement of Native Americans but the development of the slave trade which brought more free labor

Notes Find the absolute largest onion you can find, roughly weighing about 450g (1lbs)

This element is considered a potent carcinogen

Though not monitored in the United States, betel quid is commonly used in other regions

The level of evidence you need also depends on the total value of the items you want to claim these rates for