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Bernier FP, Snyder FF, McLeod DR: Deficiency of 5-oxoprolinase in an 8-year-old with developmental delay

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It is the same logic as a loading phase followed by a maintenance phase in many research protocols: front-load to establish, then hold with less

Importantly, amylin-responsive neurons in the AP do not express co-receptors for GLP-1 and GLP-15, suggesting different primary targets of these peptides

J Biol Chem 2000