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The pertinent copper-containing enzymes such as cytochrome c oxidase (COX) [55] or copper, zinc superoxide dismutase (Cu, Zn-SOD1) [56,57,58] are involved in the mitochondrial electron transport chain [59] or in the dismutation of superoxide radical anion (O 2 - ) to hydrogen peroxide (H 2 O 2 ), respectively

The Sikiric group has proposed several overlapping mechanisms: Nitric Oxide System Multiple rodent studies from the Zagreb group show BPC-157 influences endothelial nitric oxide synthase (eNOS) activity

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