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2003 Apr 1;34(7):928-36

The term oil-free isnt regulated so companies can define it however they want

Oral administration of Immunocal for 45 days has been shown to elevate GSH levels in the brains of healthy, nontransgenic mice by up to 300% compared to casein-treated controls, demonstrating that this supplement is able to directly affect the antioxidant status of tissues in the CNS [69]

While some clinics recommend them for brightening, they carry significant risks of severe side effects, including liver and kidney damage, as well as allergic reactions

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Liu L, Hofstetter WL, Rashid A, Swisher SG , Correa AM, Ajani JA, Hamilton SR, Wu TT