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Stops mutations Stops molecules inert, preventing their destructive effects Vital for both phase I & phase II liver detoxification Induces normal p53(tumor suppressor) activity by redox modulation, which induces apoptosis in tumor cells Detoxification is another major function

Heat exposure above 30 degrees Celsius Temperatures at or above 30 degrees Celsius (86 degrees Fahrenheit) cause rapid, often irreversible degradation

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One important mechanism behind endothelial cell dysfunction in ARDS is ferroptosis, a kind of cell death caused by iron-dependent lipid peroxidation ( Figure 4 )

Melatonins role in safeguarding the BBB integrity and functionality The BBB is a highly intricate structure composed of endothelial cells, pericytes, the capillary basement membrane, and astrocyte end-feet [181]