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A network meta-analysis demonstrating the efficacy of CBT added to antipsychotics for positive symptoms of schizophrenia

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For instance, FOXO4-D-Retro-Inverso (DRI) induces the selective apoptosis of senescent cells by inhibiting the FOXO4-p53 interaction 34

The most common GABA-A receptor subunit types in the brain are 1, 2, and 2 ( GABA-B receptors (metabotropic receptors) are G-protein coupled receptors that have a negative effect on presynaptic voltage-activated Ca 2+ channels but a positive effect on postsynaptic inwardly corrected K + channels ( + channels, inactivating voltage-stalled Ca 2+ channels, and inhibiting adenylyl cyclase

Accumulation of compatible osmolytes (e.g., proline and soluble sugars), activation of enzymatic antioxidants (SOD, CAT, POD), synthesis of stress-responsive proteins, and abscisic acid (ABA)-mediated signaling collectively preserve cellular homeostasis (Table 1)

Int J Mol Sci 21(18):6669