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Interspecies scaling (for example, body-surface-area conversion) typically reduces a rodent mg/kg figure severalfold, and even a properly scaled number would still be a hypothetical exposure , not a validated dose

If anything, the presence of a quick fix increases the risk of doing too much too soon

This observation suggests that Rg5 was pharmacologically active in a wide range of concentrations of neuronal cells, from 10 6 M to 10 18 M (Figure 11c), and had a significant impact on the gene expression of hippocampal neurons

What if I need to calculate doses for an entire multi-week protocol

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