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A., Polonskaia, A

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Metabolic levels associated with MTX resistance In addition to the association between metabolic fold change and MTX resistance, we searched for correlations between metabolic concentration and resistance to MTX (expressed as IC50) at 48 and 96 hours in either the presence or absence of the drug ( Table 1 )

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Biomedicines 10 (4), 869

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Both emerged from the same scientific goal make GHRH useful as a therapeutic by overcoming its impractically short duration of action but they took different routes and reached different destinations

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for instance, a novel function for the IGF-IR in viral entry into cells has just been identified ( Several tissue-growth-related transcription factors, including androgen and estrogen receptors, high-mobility group A1 (HMBA1), Krppel-like factor 6 (KLF6), eukaryotic translation initiation factor 2 (E2F1), and c-Jun, upregulate IGF-IR expression ( 3 Post-receptor signaling The binding of IGF-I, IGF-II, or insulin ligand to the IGF-1R initiates a series of events

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