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Researchers are currently studying new therapies specifically designed for the treatment of CSU, including ligelizumab, fenebrutinib, and remibrutinib, which target anti-ige, as well as dupilumab, which targets anti-IL-4RR (217)

The cellular homeostasis between the GSH and GSSG ratio controls the cells redox level, maintained by reactions performed by glutathione reductases (GR) and glutathione peroxidases (GPX) (Mahmood et al., 2010)

Providing care management under separate Medicare and Medicaid systems creates significant administrative burdens

doi: 10.16282/j.cnki.cn11-9336/r.2017.33.147 38 GaoHLiuJFengR

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Xanthine derivatives, such as caffeine, theophylline, and other naturally occurring xanthines, have an affinity for all four receptor subtypes