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LILRB2 interacts with a variety of ligands, including SEMA4A, CD1, ANGPTL2/5, and classical and non-classical MHC I, all of which have been implicated in promoting immune inhibition within the TME [126]

The results indicated that berberine was more concentrated in RBCs than in plasma and the maximum concentration of drug loading was 0.185 g/mL, while higher concentrations have been associated with hemolysis

doi:10.1097/bor.0000000000000985 2