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Analysis of cis- and trans-acting elements in the hormone-sensitive human somatotropin gene promoter

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In murine models, CXCL10 inhibition prevented the disease and promoted repigmentation

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In nasopharyngeal carcinoma, previous research has demonstrated that nanocarriers targeting circular (circ) RNA circADARB1 can elevate intracellular iron ion concentrations, thereby promoting radiotherapy-induced ferroptosis and increasing radiosensitivity

These compounds bind to NCOA4, disrupting its interaction with FTH1 and inhibiting NCOA4-dependent ferritin autophagy, thereby reducing intracellular free iron (Fe 2 ) levels and suppressing ferroptosis ( 4.2 Lipid peroxidation-related biomarkers and OA 4.2.1 Malondialdehyde (MDA) and 4-Hydroxynonenal (4-HNE) MDA and 4-HNE are key end products of lipid peroxidation and significant markers of ferroptosis