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This nephroprotective effect is mediated by different mechanisms: reduced blood glucose levels, restoration of normal tubulo-glomerular feedback [160], reduction of glomerular hyperfiltration, increased lipolysis and weight loss [161], and suppression of inflammation and fibrosis [162, 163]

Analysis of SARS-CoV-2 isolates, namely the Wuhan strain, Delta variant, and Omicron variant, identifies differential immune profiles