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Serious or Rare Side Effects to Watch For While rare, some side effects require immediate attention
The distinction is clinically important as management strategies differ
Evidence: Well-validated across many injury types
It could mean the difference between successfully completing a gentle, five-minute movement session and triggering a debilitating, multi-day PEM crash that leaves them bedbound
In future trials it will be important to keep track of comorbidities for clinical trial design, either for the purpose of post hoc subgroup analysis or a priori subgroup recruitment, since the neuroathophysiological mechanisms in IC/ BPS patients with different co-morbidities are likely to be different
A new alternative method for testing skin irritation using a human skin model: A pilot study
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