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The principle behind the leaky gut theory is that endogenous (e.g., psychological stress, intestinal inflammation) and exogenous factors (e.g., diet, alcohol intake) can increase intestinal permeability, allowing the entrance of food antigens, commensal or pathogenic bacteria and bacterial components into the lamina propria and later on into the systemic circulation, provoking the systemic inflammation described in different disease conditions

The body is processing a wave of apoptotic cells, and this is immunologically demanding

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BDNF ELISA on hippocampal homogenate, 24-72 h post-administration

They do not have FDA approval, and it is illegal to introduce them into the body

Brotz, H., Bierbaum, G., Leopold, K., Reynolds, P.E., and Sahl, H.G., Antimicrob