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Roughly 22% of adults in the United States have reported using nicotine or tobacco products in 2021

Simmons G, et al

E-cigarette smoking was associated with cigarette smoking (aOR=2.16, 95%CI (1.18-3.95), P-value=0.013), waterpipe smoking (aOR=4.31, 95%CI (2.44-7.61), P-value 0.05)

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The statistical approach used complete case analysis to ensure that models were fitted on a complete and comparable study population, and multiple imputation for missing data was deemed unsuitable

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