Recent research has revealed a strong association between ferroptosis and the onset of several lung disorders, including acute lung injury [199,200,201], lung ischemia-reperfusion injury [202, 203], pulmonary fibrosis [204], asthma [205], pulmonary tuberculosis [206, 207], and recently, COVID-19 [208, 209]
A specific oxidoreductase, previously known as apoptosis-inducing-factor mitochondrial-2 (AIFM2), capable of recycling reduced ubiquinol (Co-enzymeQ 10 H 2 ) from ubiquinone at the expense of NAD(P)H, has been presented as a potential ferroptosis inhibitor due to the fact that its overexpression complements the loss of GPx4 in PFA1 and human fibrosarcoma (66, 67)
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And that is because the problem in autoimmune gastritis is usually not too much acid, it is rather too little